One of the earliest and most popular family strips, Toots and Casper had a long run, from 1918-1956. Here's a mid-1920s example featuring the main characters.
Board size is about 20.875 x 5.5 inches with an image area of about 19.75 x 4.75 inches. A little dirty, some light foxing, half inch tear at the bottom of panel 1 extending into the art. Personalized inscription at the bottom of panel 1.